An international team of scientists has shed new light on the earthquake that devastated Nepal in April 2015, killing more than 8,000 people. In a study published in the journal Nature Geoscience, the scientists show that a kink in the regional fault line below Nepal explains why the highest mountains in the Himalayas are seen to grow between earthquakes. The researchers, from the UK’s Centre for the Observation and Modelling of Earthquakes, Volcanoes and Tectonics (COMET), as well as academics from the USA and France, also demonstrate that the rupture on the fault stopped 11km below Kathmandu.
The researchers of the joint team from Zhejiang University, University of Leeds and University of York are currently exploring novel glucose-responsive materials for GOX-free glucose sensors which will be more sensitive and stable.
A study of 300,000 heart attack patients, led by the University of Leeds, has found rapid rates in the uptake of a treatment which improves a patient's chances of survival after a major heart attack. The research, part-funded by the British Heart Foundation and the National Institute of Health Research, showed the uptake of heart attack treatment gives nine in ten patients fighting chance of survival. The use of emergency stenting treatment (PPCI) increased from 0.1% in 2003 to 86% in 2013 for patients with STEMI - a heart attack caused by a complete blockage of a coronary artery which accounts for 25-40% of all heart attack cases in Europe.
Around 7,000 colorectal cancer survivors in the UK struggle to cope with daily life years after their diagnosis, according to new analysis led by University of Leeds researchers. The study, recently published in the Journal of Clinical Oncology and partly funded by Macmillan Cancer Support, shows that just under 1 in 6 (15%) people who survive a year to three years after a colorectal cancer diagnosis in England experience ‘social distress’, perceiving their daily social interactions to be severely negative or distressing.
A new study may have resolved a fundamental question concerning the development of Earth as a planet on which animals could flourish: what came first, increasing levels of oxygen or complex animals? Before now it was not known how quickly Earth’s oceans and atmosphere became oxygenated and if animal life expanded before or after oxygen levels rose. The new study, published in Nature Communications, shows the increase in oxygenation began significantly earlier than previously thought and occurred in fits and starts spread over a vast period.
A new £3.4 million programme will develop new tools to understand which interactions between proteins in the human body are relevant to disease. Currently, only a handful of drugs in clinical use work by targeting protein-protein interactions. The new project, which will launch on 1 February, 2016, will involve researchers from the University of Leeds, the University of Bristol and three drug discovery organisations: the Northern Institute for Cancer Research, Newcastle University; AstraZeneca; and Domainex.
Scientists have developed an innovative way of using one of the biggest problems facing health services—antibiotic resistance—to develop drugs to combat some of the most intractable diseases. The new study, from research led by Professor Sheena Radford from the University of Leeds and published in Nature Chemical Biology, outlines a way of using antibiotic resistance to find chemicals capable of stopping amyloid formation.
New research into how a plant virus assembles could lay the groundwork for future use to carry drugs into the human body. The study, by a team from the University of Leeds’ Astbury Centre for Structural Molecular Biology and the John Innes Centre in Norwich, describes the structure of an empty version of Cowpea Mosaic Virus (CPMV) and the molecular “glue” that allows the virus to build itself and encapsulate its genome. The findings, published in the journal Nature Communications and based on revolutionary new electron microscopy, may be a crucial step to eventually allowing scientists to build custom versions of the virus that can carry medicines into the body and target disease.
After many years of failed attempts, world leaders have finally signed a comprehensive deal to address climate change at COP21 in Paris. WUN was there.
As the world’s population continues to grow and the effects of global warming and climate change begin to affect crop yields, new and existing crops must be developed that are resilient to temperature extremes, drought and salinity, while also being cheap to produce. The UN Secretary-General, Ban Ki-Moon, himself, noted the scale of the problem saying “diversification of crops with legumes and other practical measures must be scaled up to end hunger while meeting the challenge of climate change”.
Scientists and world leaders are convening in Paris to tackle climate change, and the University of Leeds is well represented at the talks, offering a wealth of expertise in climate change science. Students and alumni of the University of Leeds have also created a short documentary film about the path to Paris and why this COP should be different to previous years, which failed to reach an agreement on how to address climate change. The film, called Atmosphere, is directed by postgraduate student Nick Roxburgh from the University’s School of Earth and Environment and is the result of a successful crowd-funding campaign.