Using old drugs to treat new viruses

A group of drugs already in everyday use to treat psychosis or depression may also be used to defeat deadly and emerging viruses. Researchers from the University of Leeds found that common drugs in everyday use were successful in preventing a particular virus from infecting cells, by blocking the ion channels that regulate potassium levels in those cells.

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Unravelling the secret of antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics. Proteins of the ABC-F protein family are a major source of antibiotic resistance in ‘superbugs’ such as Staphylococcus aureus, a group of bacteria that includes MRSA. The findings, published in the American Society for Microbiology journal mBio, provide the first direct evidence of how this family of proteins ‘protect’ the bacterial ribosome, the protein makers in cells, from being blocked by antibiotics.

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New study finds vitamin D3 improves heart function

A daily dose of vitamin D3 improves heart function in people with chronic heart failure, a five-year University of Leeds research project has found. Dr Klaus Witte, from the School of Medicine and Consultant Cardiologist at Leeds Teaching Hospitals NHS Trust, led the study, known as VINDICATE. He said: “This is a significant breakthrough for patients. It is the first evidence that vitamin D3 can improve heart function of people with heart muscle weakness – known as heart failure. These findings could make a significant difference to the care of heart failure patients.”

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New study on asthma provides strong argument for focusing on the environment of young men

"It has been very difficult to get these [results] published, because the concept of adolescent boys, having impact on their offspring born years later is new and editors could not believe our findings. I think that the WUN can inspire further research to support our findings and convey the new concepts to public health policy makers..."

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